BDBM428777 (R or S)-1'- (cyclopropanecarbonyl)-5-(9- ethyl-8-(2-methylpyrimidin-5- yl)-9H-purin-6-yl)-1- isopropylspiro[indoline-3,2'- pyrrolidin]-2-one::US10544147, Compound 3-10

SMILES CCn1c(nc2c(ncnc12)-c1ccc2N(C(C)C)C(=O)C3(CCCN3C(=O)C3CC3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=QBADDYDXWSOAAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 428777   

LigandPNGBDBM428777(US10544147, Compound 3-10 | (R or S)-1'- (cyclopro...)
Affinity DataIC50: 3nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent