BDBM428780 (R or S)-1''-isopropyl-5-(9- methyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl)spiro[indoline- 3,2''-pyrrolidin]-2-one::US10544147, Compound 3-13::US10544147, Compound 3-14

SMILES CC(C)N1CCCC11C(=O)Nc2ccc(cc12)-c1ncnc2n(C)c(nc12)-c1cnc(C)nc1

InChI Key InChIKey=ZRQSRGZQXDOBHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428780   

LigandPNGBDBM428780((R or S)-1''-isopropyl-5-(9- methyl-8-(2- methylpy...)
Affinity DataIC50: 2nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428780((R or S)-1''-isopropyl-5-(9- methyl-8-(2- methylpy...)
Affinity DataIC50: 45nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent