BDBM428808 (R or S)-9-ethyl-6-[3- methyl-3-(2- methylpropyl)-1,1-dioxido- 2,3-dihydro-1,2- benzisothiazol-5-yl]-8-(2- methylpyrimidin-5-yl)-9H- purine::US10544147, Compound 4-5::US10544147, Compound 4-6

SMILES CCn1c(nc2c(ncnc12)-c1ccc2c(c1)C(C)(CC(C)C)NS2(=O)=O)-c1cnc(C)nc1

InChI Key InChIKey=UIUJWVKZKKXYJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428808   

LigandPNGBDBM428808(US10544147, Compound 4-5 | (R or S)-9-ethyl-6-[3- ...)
Affinity DataIC50: 6nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428808(US10544147, Compound 4-5 | (R or S)-9-ethyl-6-[3- ...)
Affinity DataIC50: 55nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent