BDBM428819 6-(9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl)-4-methyl-4- phenyl-1,4-dihydro-2H- benzo[d][1,3]oxazin-2-one::US10544147, Compound 4-16

SMILES CCn1c(nc2c(ncnc12)-c1ccc2NC(=O)OC(C)(c3ccccc3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=OQWPBTMLLNMDRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 428819   

LigandPNGBDBM428819(US10544147, Compound 4-16 | 6-(9-ethyl-8-(2- methy...)
Affinity DataIC50: 3nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent