BDBM428824 (R or S)-3-(1- cyclopropylethyl)-5-[9- ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]-1,3- benzoxazol-2(3H)-one::US10544147, Compound 5-5::US10544147, Compound 5-6

SMILES CCn1c(nc2c(ncnc12)-c1ccc2oc(=O)n(C(C)C3CC3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=TYIFZEMNAFOHEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428824   

LigandPNGBDBM428824(US10544147, Compound 5-5 | (R or S)-3-(1- cyclopro...)
Affinity DataIC50: 5nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428824(US10544147, Compound 5-5 | (R or S)-3-(1- cyclopro...)
Affinity DataIC50: 42nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent