BDBM428826 (R or S)-1-(1- cyclopropylethyl)-6-[9- ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]-1,3-dihydro- 2H-benzimidazol-2-one::US10544147, Compound 5-7::US10544147, Compound 5-8

SMILES CCn1c(nc2c(ncnc12)-c1ccc2[nH]c(=O)n(C(C)C3CC3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=ZZUSCHDZBPZFEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428826   

LigandPNGBDBM428826(US10544147, Compound 5-7 | (R or S)-1-(1- cyclopro...)
Affinity DataIC50: 3nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428826(US10544147, Compound 5-7 | (R or S)-1-(1- cyclopro...)
Affinity DataIC50: 24nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent