BDBM429454 3'-amino-N3-cyclopropyl- 5-fluoro-6-methyl-N4'-neo pentyl-[1,1'-biphenyl]-3,4' -dicarboxamide::US10550073, Example 42

SMILES Cc1c(F)cc(cc1-c1ccc(C(=O)NCC(C)(C)C)c(N)c1)C(=O)NC1CC1

InChI Key InChIKey=SOCQHADKVMAWRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429454   

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM429454(3'-amino-N3-cyclopropyl- 5-fluoro-6-methyl-N4'-neo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Experimental Method: 4-hydroxydiclofenac (the substrate for CYP450 and 2C9 enzymes) and different doses of compounds were added into human liver micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent