BDBM429865 N-(3-bromo-4-fluorophenyl)-N'- hydroxy-4-[(2-{[(E)-1- (methylamino)-2- nitroethenyl]amino}ethyl)sulfanyl]- 1,2,5-oxadiazole-3- carboximidamide::US10538497, Example 60

SMILES CN\C(NCCSc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O)=C/[N+]([O-])=O

InChI Key InChIKey=FIQCABJFGKRIAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429865   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429865(US10538497, Example 60 | N-(3-bromo-4-fluorophenyl...)
Affinity DataIC50: 36.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent