BDBM429891 N-(3-bromo-4-fluorophenvl)-N'- hydroxy-4-({[(2S)-5- oxopyrrolidin-2- yl]methyl}sulfanyl)-1,2,5- oxadiazole-3-carboximidamide::US10538497, Example 84

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1SC[C@@H]1CCC(=O)N1

InChI Key InChIKey=SLLXVGYMAFUANL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429891   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429891(US10538497, Example 84 | N-(3-bromo-4-fluorophenvl...)
Affinity DataIC50: 37.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent