BDBM429905 N-(3-bromo-4-fluorophenyl)-N'- hydroxy-4-{[2-({2-[(1- methylethyl)amino]-3,4- dioxocyclobut-1-en-1- yl}amino)ethyl]sulfanyl}-1,2,5- oxadiazole-3-carboximidamide::US10538497, Example 94

SMILES CC(C)Nc1c(NCCSc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)c(=O)c1=O

InChI Key InChIKey=YZRCFGGUZOGJOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429905   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429905(US10538497, Example 94 | N-(3-bromo-4-fluorophenyl...)
Affinity DataIC50: 26.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent