BDBM429906 N-(3-bromo-4-fluorophenyl)-4- {[2-({3,4-dioxo-2-[(pyridin-4- ylmethyl)amino]cyclobut-1-en- 1-yl}amino)ethyl]sulfanyl}-N'- hydroxy-1,2,5-oxadiazole-3- carboximidamide::US10538497, Example 95

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1SCCNc1c(NCc2ccncc2)c(=O)c1=O

InChI Key InChIKey=ZTIGOTWOKUPOOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429906   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429906(US10538497, Example 95 | N-(3-bromo-4-fluorophenyl...)
Affinity DataIC50: 27.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent