BDBM429909 N-(3-bromo-4-fluorophenyl)-N'- hydroxy-4-{[(4-methyl-5-oxo- 4,5-dihydro-1H-1,2,4-triazol-3- yl)methyl]sulfanyl}-1,2,5- oxadiazole-3-carboximidamide::US10538497, Example 98

SMILES Cn1c(CSc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)n[nH]c1=O

InChI Key InChIKey=HMWGCTYZYICOLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429909   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429909(US10538497, Example 98 | N-(3-bromo-4-fluorophenyl...)
Affinity DataIC50: 37.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent