BDBM429925 2-({4-[N-(3-bromo-4- fluorophenyl)-N'- hydroxycarbamimidoyl]-1,2,5- oxadiazol-3-yl}sulfanyl)-N- cyclobutylacetamide::US10538497, Example 114

SMILES Fc1ccc(NC(=N)c2nonc2SCC(=O)NC2CCC2)cc1Br

InChI Key InChIKey=NDSQJSAQQPRLOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429925   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429925(US10538497, Example 114 | 2-({4-[N-(3-bromo-4- flu...)
Affinity DataIC50: 36.9nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent