BDBM429941 N-(3-bromo-4-fluorophenyl)-N'- hydroxy-4-[(2-{[(tetrahydro-2H- pyran-4- ylmethyl)carbamoyl]amino}ethyl) sulfanyl]-1,2,5-oxadiaxole-3- carboximidamide::US10538497, Example 130

SMILES Fc1ccc(NC(=N)c2nonc2SCCNC(=O)NCC2CCOCC2)cc1Br

InChI Key InChIKey=UBLNFNBECGUOCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429941   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429941(US10538497, Example 130 | N-(3-bromo-4-fluoropheny...)
Affinity DataIC50: 37nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent