BDBM430048 (R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperidin-1-yl)-4H-1,2,4-triazol-3-amine ::US10538508, Example 24

SMILES Nc1nnc([nH]1)N1CCC(CC1)N1CCC[C@@H]1c1cccc(Cl)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 430048   

TargetChitotriosidase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

US Patent
LigandPNGBDBM430048((R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperi...)
Affinity DataIC50: <100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcidic mammalian chitinase(Homo sapiens (Human))
Oncoarendi Therapeutics

US Patent
LigandPNGBDBM430048((R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperi...)
Affinity DataIC50: <100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent