BDBM430082 5-((6-chloropyridin-3-yl)methoxy)-4-(4-fluorophenyl)picolinamide::US10538491, Compound 8

SMILES NC(=O)c1cc(c(OCc2ccc(Cl)nc2)cn1)-c1ccc(F)cc1

InChI Key InChIKey=CEXVTZJWJYYGLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430082   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430082(US10538491, Compound 8 | 5-((6-chloropyridin-3-yl)...)
Affinity DataIC50: 429nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent