BDBM430126 4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide::US10538491, Compound 52

SMILES Cn1ccc(COc2cnc(cc2-c2ccc(F)cc2)C(N)=O)n1

InChI Key InChIKey=SSSNPJKQBYVHBV-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 430126   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 66nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 78nMAssay Description:Negative allosteric modulation of mGlu2R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu6R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu3R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu7R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu5R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu8R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu4R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of mGlu1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed