BDBM43021 3-[(5-bromothiophene-2-carbonyl)amino]thiophene-2-carboxylic acid methyl ester::3-[[(5-bromo-2-thiophenyl)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester::MLS000538431::SMR000144468::cid_1246013::methyl 3-[(5-bromanylthiophen-2-yl)carbonylamino]thiophene-2-carboxylate::methyl 3-[(5-bromothiophene-2-carbonyl)amino]thiophene-2-carboxylate::methyl 3-{[(5-bromo-2-thienyl)carbonyl]amino}-2-thiophenecarboxylate

SMILES COC(=O)c1sccc1NC(=O)c1ccc(Br)s1

InChI Key InChIKey=LUQHYSXMPGKDPT-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 43021   

TargetNuclear receptor coactivator 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43021(SMR000144468 | 3-[[(5-bromo-2-thiophenyl)-oxomethy...)
Affinity DataEC50:  8.67E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43021(SMR000144468 | 3-[[(5-bromo-2-thiophenyl)-oxomethy...)
Affinity DataEC50: <8.82E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43021(SMR000144468 | 3-[[(5-bromo-2-thiophenyl)-oxomethy...)
Affinity DataEC50:  1.22E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43021(SMR000144468 | 3-[[(5-bromo-2-thiophenyl)-oxomethy...)
Affinity DataIC50: 1.86E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43021(SMR000144468 | 3-[[(5-bromo-2-thiophenyl)-oxomethy...)
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43021(SMR000144468 | 3-[[(5-bromo-2-thiophenyl)-oxomethy...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay