BDBM430254 N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methylamino)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)ethyl)phenyl)-2-cyano-4-ethoxy-4-methylpent-2-enamide::US10538517, Compound Table 2.27

SMILES CCOC(C)(C)C=C(C#N)C(=O)Nc1ccc(CCn2c3nc(NC)ncc3cc(-c3cc(OC)cc(OC)c3Cl)c2=O)cc1

InChI Key InChIKey=NMFBWAYHGDXDMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430254   

TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

US Patent
LigandPNGBDBM430254(N-(4-(2-(6-(2-chloro-3,5-dimethoxyphenyl)-2-(methy...)
Affinity DataIC50: 4.90nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent