BDBM430335 2-chloro-N-[3-(1-hydroxy-1- methylethyl)-7-phenylimidazo[1,2- a]pyridin-8-yl]-5-(1-methyl-1H-pyrazol- 3-yl)-4-(trifluoromethyl)benzamide::US10556900, Compound 17

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2c(ccn3c(cnc23)C(C)(C)O)-c2ccccc2)c(Cl)cc1C(F)(F)F

InChI Key InChIKey=YNRLMRULUXSZAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430335   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430335(2-chloro-N-[3-(1-hydroxy-1- methylethyl)-7-phenyli...)
Affinity DataIC50: 1.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent