BDBM430340 8-({[2-fluoro-5-(1-methyl-1H-pyrazol-3- yl)-4- (trifluoromethyl)phenyl]carbonyl}amino)- 7-phenylimidazo[1,2-a]pyridine-3- carboxamide::US10556900, Compound 22

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2c(ccn3c(cnc23)C(N)=O)-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=HWGNQLMXQLQQPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430340   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430340(8-({[2-fluoro-5-(1-methyl-1H-pyrazol-3- yl)-4- (tr...)
Affinity DataIC50: 0.510nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent