BDBM430351 3-(1-methyl-1H-pyrazol-3-yl)-N-(7- phenyl[1,2,4]triazolo[4,3-c]pyrimidin-8- yl)-4-(trifluoromethyl)benzamide::US10556900, Compound 33

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1c(ncn2cnnc12)-c1ccccc1

InChI Key InChIKey=VPBAUAQJXXVTRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430351   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430351(3-(1-methyl-1H-pyrazol-3-yl)-N-(7- phenyl[1,2,4]tr...)
Affinity DataIC50: 6.30nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent