BDBM430355 N-[3-(1-hydroxy-1- methylethyl)-6- phenylpyrazolo[1,5- a]pyridin-7-yl]-3-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US10556900, Compound 37

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1c(ccc2c(cnn12)C(C)(C)O)-c1ccccc1

InChI Key InChIKey=BJRVPNJQYDNFBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430355   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430355(N-[3-(1-hydroxy-1- methylethyl)-6- phenylpyrazolo[...)
Affinity DataIC50: 4.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent