BDBM430358 N-[3-(hydroxymethyl)-6- phenylpyrazolo[1,5- a]pyridin-7-yl]-3-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US10556900, Compound 40

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1c(ccc2c(CO)cnn12)-c1ccccc1

InChI Key InChIKey=JLQCRGPDDHBDKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430358   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430358(N-[3-(hydroxymethyl)-6- phenylpyrazolo[1,5- a]pyri...)
Affinity DataIC50: 1.40nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent