BDBM430690 (8-methyl-3-(2-morpholinothiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)(4-(thiophen-2-yl)phenyl)methanone::US10544150, Compound 56

SMILES CC1N(CCn2c1nnc2-c1csc(n1)N1CCOCC1)C(=O)c1ccc(cc1)-c1cccs1

InChI Key InChIKey=KZIWVFUQLZJSRF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430690   

TargetNeuromedin-K receptor(Human)
Ogeda

US Patent
LigandPNGBDBM430690(US10544150, Compound 56 | (8-methyl-3-(2-morpholin...)
Affinity DataKi: <500nMAssay Description:The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent