BDBM431280 US10550105, Example 225::US10870641, Example 225::US11014913, Example 225

SMILES CC(=O)N1CCC(Oc2cccc3c2CN(c2cn[nH]c(=O)c2C(F)(F)F)C3)CC1

InChI Key InChIKey=OZPUKHIKMUJBIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 431280   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 431280BDBM431280(US10550105, Example 225 | US10870641, Example 225 ...)
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 431280BDBM431280(US10550105, Example 225 | US10870641, Example 225 ...)
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 431280BDBM431280(US10550105, Example 225 | US10870641, Example 225 ...)
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent