BDBM431872 1-(3-(((1S,4R,5R)-4-hydroxy-2-methyl-3-oxo-2- azabicyclo[3.1.0]hexan-4-yl)ethynyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-3-carboxamide::US10550117, Compound 2

SMILES CN1[C@H]2C[C@H]2[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3cccnc23)C1=O

InChI Key InChIKey=GMAWUPHGBKLOEK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 431872   

LigandPNGBDBM431872(1-(3-(((1S,4R,5R)-4-hydroxy-2-methyl-3-oxo-2- azab...)
Affinity DataKi:  4.30nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent