BDBM432112 (S)-2-(tert-butoxy)-2-(5-(2-(4-chlorobenzo[d]thiazol-2-yl)-1,2,3,4- tetrahydroisoquinolin-6-yl)-4-(4,4-dimethylpiperidin-1-yl)-2,6- dimethylpyridin-3-yl)acetic acid::US10577353, Compound 7

SMILES Cc1nc(C)c(-c2ccc3CN(CCc3c2)c2nc3c(Cl)cccc3s2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key InChIKey=DKHYRIICYLXFHT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432112   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432112(US10577353, Compound 7 | (S)-2-(tert-butoxy)-2-(5-...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent