BDBM432127 (S)-2-(5-(2-(5H-pyrrolo[3,2-d]pyrimidin-4-yl)-1,2,3,4- tetrahydroisoquinolin-6-yl)-4-(4,4-dimethylpiperidin-1-yl)-2,6- dimethylpyridin-3-yl)-2-(tert-butoxy)acetic acid::US10577353, Compound 22::US10577353, Compound 26

SMILES Cc1nc(C)c([C@H](OC(C)(C)C)C(=O)O)c(N2CCC(C)(C)CC2)c1-c1ccc2c(c1)CCN(c1ncnc3cc[nH]c13)C2

InChI Key InChIKey=IMXJSJGKJBZUAI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 432127   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandChemical structure of BindingDB Monomer ID 432127BDBM432127(US10577353, Compound 26 | (S)-2-(5-(2-(5H-pyrrolo[...)
Affinity DataEC50:  20nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandChemical structure of BindingDB Monomer ID 432127BDBM432127(US10577353, Compound 26 | (S)-2-(5-(2-(5H-pyrrolo[...)
Affinity DataEC50:  286nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent