BDBM432267 N-{6-[3-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl]pyridin-2-yl]-N-(1-methylpiperidin-4-::US10577360, Example 130

SMILES CN1CCC(CC1)N(C(=O)c1cccs1)c1cccc(n1)-c1cccc(c1)-c1nnc(C)o1

InChI Key InChIKey=IXQDBAZLIFALFX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 432267   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM432267(US10577360, Example 130 | N-{6-[3-(5-Methyl-1,3,4-...)
Affinity DataKi:  300nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM432267(US10577360, Example 130 | N-{6-[3-(5-Methyl-1,3,4-...)
Affinity DataKi: >500nMAssay Description:To investigate binding properties of test compounds to human μ-opioid receptor, transfected CHO-K1 cell membranes and [3H]-DAMGO (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent