BDBM432305 US10577361, E15

SMILES Cn1c(SCCCN2CCO[C@H](C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccc(cc1)-c1ncco1

InChI Key InChIKey=PMZOPKCHYGDQPO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 432305   

TargetD(3) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM432305(US10577361, E15)
Affinity DataKi:  437nMAssay Description:[3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM432305(US10577361, E15)
Affinity DataKi:  1.55E+4nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent