BDBM43263 1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one::1-(4-nitrophenyl)-3-phenyl-prop-2-yn-1-one::1-(4-nitrophenyl)-3-phenylprop-2-yn-1-one::MLS000535276::SMR000142713::cid_891179

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)C#Cc1ccccc1

InChI Key InChIKey=YBONEMWOTSDHME-UHFFFAOYSA-N

Data  1 KI  2 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 43263   

LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataKi:  760nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-2A(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKappa-type opioid receptor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataIC50:  9.68E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-7a(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  8.38E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataEC50:  6.48E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKappa-type opioid receptor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM43263(1-(4-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(4-n...)
Affinity DataIC50:  1.63E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay