BDBM433086 N-((3S,4R)-1-(((1r,4S)-4- aminocyclohexyl)sulfonyl)-3- methylpiperidin-4-yl)-5- cyclopropylisoxazole-3-carboxamide::US10577363, Compound 790

SMILES C[C@H]1CN(CC[C@H]1NC(=O)c1cc(on1)C1CC1)S(=O)(=O)[C@H]1CC[C@H](N)CC1

InChI Key InChIKey=UHZLPXZYYDMLGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433086   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM433086(US10577363, Compound 790 | N-((3S,4R)-1-(((1r,4S)-...)
Affinity DataIC50: 1.81nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent