BDBM433289 N-methyl-1-(3-(1-(6-methylpyridin-2-yl)-1H-indazol-6-yl)phenyl)methanamine::US10577367, Example 18

SMILES CNCc1cccc(n1)-c1ccc2cnn(-c3cccc(C)n3)c2c1

InChI Key InChIKey=WDXYGHYBJMJJJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433289   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM433289(US10577367, Example 18 | N-methyl-1-(3-(1-(6-methy...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
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Date in BDB:
11/21/2020
Entry Details
US Patent