BDBM433294 6-((2-amino-3- chloropyridin-4-yl)thio)-3- ((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5]decan-8- yl)pyrazin-2(1H)-one::US10561655, Compound 77

SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc(N)c3Cl)[nH]c2=O)[C@@H]1N

InChI Key InChIKey=KGPHRRMHMZRZFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433294   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433294(US10561655, Compound 77 | 6-((2-amino-3- chloropyr...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent