BDBM433298 N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl)-6- oxo-1,6-dihydropyrazin-2- yl)thio)-2-chlorophenyl)- 4-hydroxy-1,5,5-trimethyl- 2-oxo-2,5-dihydro-1H- pyrrole-3-carboxamide::US10561655, Compound 28

SMILES CN1C(=O)C(C(=O)Nc2cccc(Sc3cnc(N4CCC(C)(CN)CC4)c(=O)[nH]3)c2Cl)=C(Cl)C1(C)C

InChI Key InChIKey=CVJFGOUNTMTWOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433298   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433298(US10561655, Compound 28 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent