BDBM433312 3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5]decan-8-yl)- 6-((3-chloro-2- fluoropyridin-4- yl)thio)pyrazin-2(1H)-one::US10561655, Compound 83

SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc(F)c3Cl)[nH]c2=O)[C@@H]1N

InChI Key InChIKey=DXVBHTAAPLIMDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433312   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433312(US10561655, Compound 83 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent