BDBM433315 (S)-3-(1-amino-1,3- dihydrospiro[indene-2,4'- piperidin]-1'-yl)-6-((2,3- dichlorophenyl)thio) pyrazin-2(1H)-one::US10561655, Compound 108

SMILES N[C@@H]1c2ccccc2CC11CCN(CC1)c1ncc(Sc2cccc(Cl)c2Cl)[nH]c1=O

InChI Key InChIKey=UNRCWEPFQCACOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433315   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433315(US10561655, Compound 108 | (S)-3-(1-amino-1,3- dih...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent