BDBM433317 (S)-3-(4-amino-2-oxa-8- azaspiro[4.5]decan-8-yl)- 6-((2,3-dichloropyridin-4- yl)thio)pyrazin-2(1H)-one::US10561655, Compound 88

SMILES N[C@@H]1COCC11CCN(CC1)c1ncc(Sc2ccnc(Cl)c2Cl)[nH]c1=O

InChI Key InChIKey=HCCZQXQCSXBLIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433317   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433317(US10561655, Compound 88 | (S)-3-(4-amino-2-oxa-8- ...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent