BDBM433322 (6aR,9aS)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(isopropylthio)-2-(4-(6-fluoropyridin-2-yl)benzyl)-cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one::US10561656, Example 3-B

SMILES CC(C)Sc1c2c(nn1Cc1ccc(cc1)-c1cccc(F)n1)N1[C@H]3CCC[C@H]3N=C1N(C)C2=O

InChI Key InChIKey=XRZKIVRXPTZVAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433322   

LigandPNGBDBM433322(US10561656, Example 3-B | (6aR,9aS)-5,6a,7,8,9,9a-...)
Affinity DataIC50: 6nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent