BDBM433552 US10562853, Compound 72

SMILES Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCCOc2cccc(Cl)n2)CC1

InChI Key InChIKey=VTBXTDAXQSIVGY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 433552   

Target5-hydroxytryptamine receptor 1A(Human)
Neurolixis

US Patent
LigandPNGBDBM433552(US10562853, Compound 72)
Affinity DataKi:  0.200nMAssay Description:5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Human)
Neurolixis

US Patent
LigandPNGBDBM433552(US10562853, Compound 72)
Affinity DataKi:  180nMAssay Description:Alpha1-adrenergic Receptor: Radioligand binding was performed using tissue (rat cortex). All assays were carried out in duplicates. 50 μL workin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Neurolixis

US Patent
LigandPNGBDBM433552(US10562853, Compound 72)
Affinity DataKi: >1.00E+3nMAssay Description:D2 Dopamine Receptor:Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human D2 receptor. All assays we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent