BDBM433587 5-[3-(1-Ethyl-1H-indol-2-yl)piperidine-1-carbonyl]-N-methylpyridazin-3-amine::US10562882, Example 12

SMILES CCn1c(cc2ccccc12)C1CCCN(C1)C(=O)c1cnnc(NC)c1

InChI Key InChIKey=FQAQSPJNTGVJRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433587   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433587(US10562882, Example 12 | 5-[3-(1-Ethyl-1H-indol-2-...)
Affinity DataIC50: 480nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent