BDBM433592 1-Methyl-4-{3-[1-(propan-2-yl)-1H-indol-2-yl]piperidine-carbonyl}-1H-pyrazol-3-amine::US10562882, Example 16

SMILES CC(C)n1c(cc2ccccc12)C1CCCN(C1)C(=O)c1cn(C)nc1N

InChI Key InChIKey=LTMALLIGWZECFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433592   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433592(US10562882, Example 16 | 1-Methyl-4-{3-[1-(propan-...)
Affinity DataIC50: 1.44E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent