BDBM433636 5-[3-(5-Chloro-3-methylpyridin-2-yl)piperidine-1-carbonyl]-N,N-dimethylpyridazin-3-amine::US10562882, Example 28

SMILES CN(C)c1cc(cnn1)C(=O)N1CCCC(C1)c1ncc(Cl)cc1C

InChI Key InChIKey=ITIQXLMNOPDYIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433636   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433636(5-[3-(5-Chloro-3-methylpyridin-2-yl)piperidine-1-c...)
Affinity DataIC50: 1.04E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent