BDBM434527 US10562893, Compound 31

SMILES O[C@H]1CC[C@@H](CC1)NCc1ccc2n(c(NC(=O)c3ccc(s3)C(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1

InChI Key InChIKey=XHCQPTWBMGYGLR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434527   

TargetTyrosine-protein kinase TXK(Human)
Gb005

US Patent
LigandPNGBDBM434527(US10562893, Compound 31)
Affinity DataEC50: <10nMAssay Description:RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Gb005

US Patent
LigandPNGBDBM434527(US10562893, Compound 31)
Affinity DataEC50: <10nMAssay Description:ITK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent