BDBM434563 US10562900, Example 47

SMILES CCN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(ccc12)-c1c(F)c(OC)cc(OC)c1F

InChI Key InChIKey=NCUDMWQOOHSIFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434563   

TargetFibroblast growth factor receptor 2(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434563(US10562900, Example 47)
Affinity DataIC50: 100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434563(US10562900, Example 47)
Affinity DataIC50: 100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent