BDBM434564 US10562900, Example 48

SMILES COc1cc(OC)c(F)c(c1)-c1ccc2c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)n[nH]c2n1

InChI Key InChIKey=OHAGIYCRMMGRHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434564   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434564(US10562900, Example 48)
Affinity DataIC50: 100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434564(US10562900, Example 48)
Affinity DataIC50: 100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent