BDBM434720 BDBM434721::US10562902, Compound 126

SMILES CNC(=O)c1csc(Nc2nc(O[C@H]3CCOC3)c3n(ccc3n2)-c2ccoc2)c1

InChI Key InChIKey=HYPQPLOCIZTAIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434720   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM434720(BDBM434721 | US10562902, Compound 126)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM434720(BDBM434721 | US10562902, Compound 126)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent