BDBM4349 (2E)-2-cyano-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 33

SMILES COc1cc(\C=C(/C#N)C(O)=O)cc(OC)c1O

InChI Key InChIKey=NDBVLMVMOJCWHU-FPYGCLRLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4349   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4349((2E)-2-cyano-3-(4-hydroxy-3,5-dimethoxyphenyl)prop...)
Affinity DataKi:  2.64E+5nM IC50:  7.00E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed