BDBM435027 (2S,3S)-1-(benzofuran-2-ylsulfonyl)-3-hydroxy-N-[[3- isopropyl-2,4-dioxo-1-[4-(trifluoromethyl)phenyl]- pyrimidin-5-yl]methyl]pyrrolidine-2-carboxamide::US10584116, Example 7

SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=YBVLXHRURDNMHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435027   

LigandPNGBDBM435027(US10584116, Example 7 | (2S,3S)-1-(benzofuran-2-yl...)
Affinity DataIC50: 220nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent